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 　　英國首相卡梅倫制定了一個旨在使英國走在世界生物醫(yī)藥基因組研究前列的計(jì)劃。英國計(jì)劃投入1億6千萬美元測定超過10萬個完整基因組序列。一家由英國衛(wèi)生部成立的名為Genomics England的生物信息學(xué)公司將要把卡梅倫的這一設(shè)想變成現(xiàn)實(shí)。不過現(xiàn)在看來，1億6千萬美元的投資相對于10萬個基因組的目標(biāo)還是顯得不足。如何有效利用這筆資金也成為了一個重要問題。

　　詳細(xì)英文報(bào)道：

　　In December, Prime Minister David Cameron outlined his plan to turn the United Kingdom into a world leader in medical genomics, but beyond the headline-grabbing numbers--$160 million to sequence 100,000 whole genomes--details were scarce. Now, the group tasked with the project has spoken up.

　　The headline figures remain the same, with Genomics England--the company created by the Department of Health to enact Cameron's vision--committing to deliver 100,000 whole genomes by 2017. Exactly how it will achieve this ambitions target is still being decided, but at its first 'Town Hall' outreach event, Genomics England discussed creating several sequencing centers in partnership with industry, Caroline Wright, a molecular scientist and writer at Genomes Unzipped, reports.

　　With just $160 million in funding, Genomics England will have to use its money well to achieve the 100,000 genome target and is promoting competition between next-generation sequencing providers to drive down costs. At this stage, it is unclear who is in the running. More details of the project are expected to emerge as Genomics England works through an 18-month pilot project, during which it will sequence a few thousand genomes. The pilot will establish processes for selecting patients with rare inherited illnesses, cancer and infectious diseases--the three areas of focus--for sequencing.

　　Genomics England has already decided to store the data inside the National Health Service (NHS) firewall. Once generated, Genomics England will link data to patient records for clinical use and make it available for research in an anonymized form. A potential stumbling block is NHS' poor track record with IT projects. An attempt to establish electronic health records went well over budget and failed to deliver many of its promised improvements.